⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034082 | 0.86 | TSHR (0.36) | — | |
| SCHEMBL93127 | 0.85 | — | — | |
| SCHEMBL93267 | 0.83 | ADH1B (0.45) | — | |
| SCHEMBL13037388 | 0.83 | ADH1B (0.45) | — | |
| SCHEMBL2108219 | 0.81 | ADH1B (0.48) | — | |
| SCHEMBL93171 | 0.81 | ADH1B (0.48) | — | |
| SCHEMBL2110531 | 0.81 | ADH1B (0.48) | — | |
| SCHEMBL14093584 | 0.81 | ADH1B (0.48) | — | |
| SCHEMBL2109688 | 0.81 | ADH1B (0.48) | — | |
| SCHEMBL8810975 | 0.81 | ADH1B (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250212873-A1 | VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-07-03 | — | — | US | claimed |
| CN-110981873-B | Preparation method for synthesizing pyrroloquinoline quinone by five-step method | 江西农业大学 | 2025-01-24 | — | — | CN | claimed |
| EP-4482306-A1 | VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-01 | — | — | EP | claimed |
| CN-114014878-B | Conjugated alkenyl zinc reagent, preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | claimed |
| CN-116535439-B | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2024-05-28 | — | — | CN | claimed |
| WO-2023192424-A1 | VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-05 | — | — | WO | claimed |
| CN-116535439-A | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2023-08-04 | — | — | CN | claimed |
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | claimed |
| CN-116272737-A | Continuous flow preparation method of 2-aryl carboxylic acid compound | 复旦大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116003462-A | Silicon-based substituted chiral amine and preparation method and application thereof | 南开大学 | 2023-04-25 | — | — | CN | claimed |
| US-9108995-B2 | Spirobenzylamine-phosphine, preparation method therefor and use thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2015-08-18 | — | — | US | claimed |
| EP-2272853-B1 | SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2014-08-27 | — | — | EP | claimed |
| US-20140194638-A1 | Spirobenzylamine-Phosphine, Preparation Method Therefor And Use Thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2014-07-10 | — | — | US | claimed |
| EP-2752419-A1 | SPIROBENZYLAMINE-PHOSPHINE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2014-07-09 | — | — | EP | claimed |
| US-8450493-B2 | Spiro phosphine-oxazoline, preparation method and application thereof | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2013-05-28 | — | — | US | claimed |
| US-20110118472-A1 | Spiro Phosphine-Oxazoline, Preparation Method and Application thereof | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-05-19 | — | — | US | claimed |
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-04-21 | — | — | US | claimed |
| EP-2275398-A1 | APPLICATION OF THE IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION FOR UNSATURATED CARBOXYLIC ACID | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-01-19 | — | — | EP | claimed |
| EP-2272853-A1 | SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-01-12 | — | — | EP | claimed |
| US-4225513-A | OF SECONDARY ALCOHOLS TO FORM KETONES | UNION CARBIDE CORPORATION (US) | 1980-09-30 | — | — | US | claimed |