Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737161 | 1.00 | MGLL (0.60) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL28737165 | 1.00 | MGLL (0.60) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL2711052 | 1.00 | MGLL (0.60) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL23391365 | 0.96 | LPAR1 (0.57) | — | |
| SCHEMBL1374046 | 0.96 | LPAR1 (0.57) | — | |
| SCHEMBL30864381 | 0.92 | LPAR1 (0.61) | — | |
| SCHEMBL258047 | 0.92 | LPAR1 (0.61) | — | |
| SCHEMBL471851 | 0.92 | LPAR1 (0.61) | — | |
| SCHEMBL21582226 | 0.92 | LPAR1 (0.61) | — | |
| SCHEMBL4979121 | 0.92 | LPAR1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445494-A1 | TREATMENT OF INSULIN RESISTANCE AND OBESITY BY STIMULATING GLP-1 RELEASE | Københavns Universitet (DK) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149170-A1 | TREATMENT OF INSULIN RESISTANCE AND OBESITY BY STIMULATING GLP-1 RELEASE | Københavns Universitet (DK) | 2010-12-29 | — | — | WO | disclosed |