Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334473 | 0.81 | LMNA (0.37) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15831731 | 0.81 | LMNA (0.37) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL17392918 | 0.80 | KDM4E (0.37) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8273057 | 0.80 | LMNA (0.36) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL17392916 | 0.80 | KDM4E (0.37) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9334509 | 0.80 | KDM4E (0.37) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL697217 | 0.77 | KDM4E (0.35) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30753324 | 0.77 | KDM4E (0.37) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15831734 | 0.77 | KDM4E (0.35) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25232302 | 0.74 | CYP2D6 (0.36) | LMNAKDM4ECYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |