Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27326098 | 0.74 | PDK2 (0.37) | ESR1ESR2EPHX1EPHX2 | |
| SCHEMBL27326097 | 0.74 | PDK2 (0.37) | ESR1ESR2EPHX1EPHX2 | |
| SCHEMBL27115233 | 0.74 | PDK2 (0.37) | ESR1ESR2EPHX1EPHX2 | |
| SCHEMBL24333749 | 0.74 | MEN1 (0.35) | EPHX2 | |
| SCHEMBL5702065 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL23013222 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL5702261 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL20221854 | 0.72 | LMNA (0.55) | NAMPT | |
| SCHEMBL22541499 | 0.72 | LMNA (0.44) | — | |
| SCHEMBL18701781 | 0.71 | LMNA (0.50) | EPHX2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | KHK, GCK, HK1 | ESR1 3399/4885ESR2 3135/4885EPHX1 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.