Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705157 | 1.00 | CDA (0.42) | CDALMNAGBA1LGALS3DPP4 | |
| SCHEMBL26900891 | 0.91 | CDA (0.43) | CDALMNAGBA1LGALS3 | |
| SCHEMBL23705229 | 0.91 | CDA (0.43) | CDALMNAGBA1LGALS3 | |
| SCHEMBL24256519 | 0.80 | CDA (0.63) | CDALGALS3 | |
| SCHEMBL26879327 | 0.80 | CDA (0.63) | CDALGALS3 | |
| SCHEMBL23705299 | 0.78 | LMNA (0.37) | CDALMNAGBA1LGALS3 | |
| SCHEMBL24256353 | 0.78 | LMNA (0.37) | CDALMNAGBA1LGALS3 | |
| SCHEMBL24256513 | 0.77 | CDA (0.36) | CDALMNAGBA1LGALS3 | |
| SCHEMBL24256694 | 0.77 | CDA (0.51) | CDALMNAGBA1 | |
| SCHEMBL23705041 | 0.77 | CDA (0.36) | CDALMNAGBA1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |