Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.66 |
| ▸ | ABL1 | P00519 | 4/20 | 0.66 |
| ▸ | BCR | P11274 | 4/20 | 0.66 |
| ▸ | CDK2 | P24941 | 2/20 | 0.60 |
| ▸ | CDK1 | P06493 | 2/20 | 0.60 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.59 |
| ▸ | SRC | P12931 | 3/20 | 0.58 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.58 |
| ▸ | SYK | P43405 | 1/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.57 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27115896 | 0.89 | PIK3CG (0.76) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL27116600 | 0.88 | ABL1 (0.57) | PIK3CGPIK3CAABL1BCRSMG1 | |
| SCHEMBL27116528 | 0.88 | PIK3CG (0.64) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL5733563 | 0.88 | MAPT (0.72) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL27115339 | 0.86 | PIK3CG (0.55) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL2331086 | 0.86 | PIK3CG (0.70) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL2322043 | 0.86 | PIK3CG (0.70) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL27115892 | 0.85 | ABL1 (0.59) | PIK3CGPIK3CAABL1BCRPIK3CB | |
| SCHEMBL27115444 | 0.85 | PIK3CA (0.69) | PIK3CGPIK3CAABL1BCRCDK2 | |
| Hydrochloric Acid SCHEMBL16496538 | 0.85 | PIK3CG (0.69) | PIK3CGPIK3CAABL1BCRCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |