Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.70 |
| ▸ | ABL1 | P00519 | 3/20 | 0.70 |
| ▸ | BCR | P11274 | 3/20 | 0.70 |
| ▸ | CDK2 | P24941 | 3/20 | 0.64 |
| ▸ | CDK1 | P06493 | 2/20 | 0.64 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 3/20 | 0.62 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.62 |
| ▸ | SYK | P43405 | 2/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.60 |
| ▸ | RET | P07949 | 1/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.55 |
| ▸ | PLK1 | P53350 | 2/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322043 | 1.00 | PIK3CG (0.70) | PIK3CGPIK3CAABL1BCRCDK2 | |
| Hydrochloric Acid SCHEMBL16496538 | 0.99 | PIK3CG (0.69) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL27115444 | 0.88 | PIK3CA (0.69) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL7467324 | 0.88 | ABL1 (0.76) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL2329574 | 0.87 | ABL1 (0.61) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL7813342 | 0.87 | PIK3CA (0.67) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL2328157 | 0.87 | CAMK2D (0.70) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL27115445 | 0.86 | PIK3CG (0.66) | PIK3CGPIK3CAABL1BCRCDK2 | |
| Water SCHEMBL7813855 | 0.85 | PIK3CA (0.65) | PIK3CGPIK3CAABL1BCRCDK2 | |
| SCHEMBL2324992 | 0.85 | PIK3CG (0.76) | PIK3CGPIK3CAABL1BCRCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | claimed |
| WO-1999035140-A1 | PYRIDINYLPYRIMIDINE AMINES AS IMMUNOGLOBULINE E (IgE) SYNTHESIS INHIBITORS | NOVARTIS AG (CH) | 1999-07-15 | — | — | WO | claimed |
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| EP-2356102-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055114-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
| WO-1999035140-A1 | PYRIDINYLPYRIMIDINE AMINES AS IMMUNOGLOBULINE E (IgE) SYNTHESIS INHIBITORS | NOVARTIS AG (CH) | 1999-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | PRXL2A, AZI2, PIR | PIK3CG 2330/4885PIK3CA 1630/4885ABL1 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.