Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 7/20 | 0.55 |
| ▸ | BCR | P11274 | 7/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | PRKACG | P22612 | 1/20 | 0.51 |
| ▸ | PRKACB | P22694 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | PRKCH | P24723 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735972 | 0.87 | PIK3CG (0.78) | PIK3CGPIK3CAPIK3CBCDK5ABL1 | |
| SCHEMBL27116349 | 0.87 | ABL1 (0.64) | PIK3CGPIK3CAPIK3CBCDK5ABL1 | |
| SCHEMBL4736185 | 0.86 | PIK3CG (0.80) | PIK3CGPIK3CAPIK3CBCDK5ABL1 | |
| SCHEMBL27116070 | 0.86 | PIK3CG (0.57) | PIK3CGPIK3CAPIK3CBCDK5ABL1 | |
| SCHEMBL27116018 | 0.83 | ABL1 (0.55) | PIK3CGPIK3CAABL1BCRSRC | |
| SCHEMBL7461678 | 0.82 | ABL1 (0.73) | ABL1BCRSRCPRKCAEGFR | |
| SCHEMBL27115671 | 0.82 | PIK3CG (0.63) | PIK3CGPIK3CAPIK3CBCDK5ABL1 | |
| SCHEMBL27116179 | 0.82 | PIK3CG (0.66) | PIK3CGPIK3CAPIK3CBCDK5ABL1 | |
| SCHEMBL27115897 | 0.81 | PIK3CG (0.69) | PIK3CGPIK3CAPIK3CBCDK5CDK4 | |
| SCHEMBL27116528 | 0.81 | PIK3CG (0.64) | PIK3CGPIK3CAPIK3CBCDK5ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |