Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223276 | 0.81 | KDM4E (0.53) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL27115085 | 0.79 | MEN1 (0.66) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL27115830 | 0.79 | KDM4E (0.54) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL10194257 | 0.75 | KDM4E (0.62) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL28864065 | 0.75 | KDM4E (0.46) | KDM4ELMNAPOLBALDH1A1 | |
| SCHEMBL27344803 | 0.74 | KDM4E (0.49) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL17788166 | 0.74 | KDM4E (0.53) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL9355962 | 0.73 | KDM4E (0.53) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL10817967 | 0.73 | HSP90AA1 (0.64) | ALDH1A1 | |
| SCHEMBL27139968 | 0.72 | DYRK1A (0.49) | LMNAMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |