Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.73 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.73 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.69 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | BCR | P11274 | 1/20 | 0.67 |
| ▸ | PRKCA | P17252 | 1/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.64 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116598 | 0.91 | PIK3CG (0.83) | PIK3CGPIK3CAPIK3CBCAMK2DDYRK1A | |
| SCHEMBL27116705 | 0.88 | PIK3CG (0.73) | PIK3CGPIK3CAPIK3CBABL1PRKCA | |
| SCHEMBL5999205 | 0.86 | PIK3CG (0.77) | PIK3CGPIK3CAPIK3CBCAMK2DABL1 | |
| SCHEMBL4735972 | 0.86 | PIK3CG (0.78) | PIK3CGPIK3CAPIK3CBCAMK2DABL1 | |
| SCHEMBL4785619 | 0.86 | PIK3CG (0.70) | PIK3CGPIK3CAPIK3CBPLK1DYRK1A | |
| SCHEMBL5733563 | 0.86 | MAPT (0.72) | PIK3CGPIK3CAPIK3CBCAMK2DABL1 | |
| SCHEMBL2942460 | 0.84 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBCAMK2DPLK1 | |
| SCHEMBL14169345 | 0.84 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CBCAMK2DABL1 | |
| SCHEMBL2939794 | 0.83 | CDK5 (0.80) | PIK3CGPIK3CAPIK3CBCAMK2DABL1 | |
| SCHEMBL12275354 | 0.83 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CBPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |