Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22321015 | 0.85 | HSD17B10 (0.53) | HSD17B10PTPN1IDO1LMNAALDH1A1 | |
| SCHEMBL30471402 | 0.85 | HSD17B10 (0.53) | HSD17B10PTPN1IDO1LMNAALDH1A1 | |
| SCHEMBL30166486 | 0.76 | MPL (0.55) | ASIC3BACE1IDO1ALDH1A1NOS3 | |
| SCHEMBL3366206 | 0.76 | ASIC3 (0.53) | ASIC3BACE1PTPN1IDO1NOS3 | |
| SCHEMBL30251342 | 0.76 | ASIC3 (0.53) | HSD17B10ASIC3BACE1PTPN1IDO1 | |
| SCHEMBL12592255 | 0.76 | ASIC3 (0.53) | HSD17B10ASIC3ALDH1A1MAPK1NOS3 | |
| SCHEMBL1915309 | 0.76 | ASIC3 (0.53) | HSD17B10ASIC3BACE1PTPN1IDO1 | |
| SCHEMBL3935260 | 0.76 | MPL (0.55) | ASIC3BACE1IDO1ALDH1A1NOS3 | |
| SCHEMBL27859531 | 0.76 | ASIC3 (0.53) | HSD17B10ASIC3IDO1LMNAALDH1A1 | |
| SCHEMBL10752750 | 0.76 | CCR1 (0.58) | HSD17B10PTPN1IDO1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630172-A1 | PRECATALYSTS FOR PREPARATION OF POLYOLEFINS AND USE THEREOF | Deutsche Institute für Textil- und Faserforschung Denkendorf (DE) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012052436-A1 | PRECATALYSTS FOR PREPARATION OF POLYOLEFINS AND USE THEREOF | DEUTSCHE INSTITUTE FÜR TEXTIL- UND FASERFORSCHUNG DENKENDORF (DE) | 2012-04-26 | — | — | WO | disclosed |