SCHEMBL27119132

SCHEMBL27119132

CCOC(=O)c1nn(-c2ccsc2)c2c1Cc1cc(OC)c(Br)cc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 2/20 0.43
▸ CDK2 P24941 2/20 0.43
▸ CCNA1 P78396 2/20 0.43
▸ ELANE P08246 2/20 0.39
▸ KCNK3 O14649 2/20 0.39
▸ ALDH1A1 P00352 4/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ CA2 P00918 2/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ LMNA P02545 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ CA1 P00915 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30759660 0.93 CCNA2 (0.47) CCNA2CDK2CCNA1ELANEKCNK3
SCHEMBL27122715 0.93 CCNA2 (0.47) CCNA2CDK2CCNA1ELANEKCNK3
SCHEMBL27119151 0.88 CA12 (0.39) CCNA2CDK2CCNA1ALDH1A1KMT2A
SCHEMBL12046682 0.86 CCNA2 (0.49) CCNA2CDK2CCNA1ELANEKCNK3
SCHEMBL16377773 0.85 CCNA2 (0.43) CCNA2CDK2CCNA1ELANEALDH1A1
SCHEMBL27118701 0.85 CCNA2 (0.43) CCNA2CDK2CCNA1KCNK3ALDH1A1
SCHEMBL27119215 0.82 PDE7A (0.38) CA2CA12CA9
SCHEMBL12046634 0.81 CCNA2 (0.44) CCNA2CDK2CCNA1ELANEKCNK3
SCHEMBL30759617 0.81 CCNA2 (0.43) CCNA2CDK2CCNA1ALDH1A1KMT2A
SCHEMBL27122717 0.81 CCNA2 (0.43) CCNA2CDK2CCNA1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR CCNA2 2070/4885CDK2 1537/4885CCNA1 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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