Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 5/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.32 |
| ▸ | PIK3R5 | Q8WYR1 | 5/20 | 0.32 |
| ▸ | PIK3R3 | Q92569 | 5/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759686 | 1.00 | GRM5 (0.37) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL20988749 | 0.95 | GRM5 (0.35) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL30759535 | 0.95 | GRM5 (0.38) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27118811 | 0.95 | GRM5 (0.38) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL31236965 | 0.91 | GRM5 (0.36) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL31758931 | 0.90 | GRM5 (0.37) | GRM5CYP11B2CYP11B1ABL1 | |
| SCHEMBL27152593 | 0.90 | GRM5 (0.37) | GRM5CYP11B2CYP11B1ABL1 | |
| SCHEMBL17381581 | 0.89 | GRM5 (0.36) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL30759547 | 0.89 | GRM5 (0.34) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27117594 | 0.89 | GRM5 (0.34) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |