Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712266 | 1.00 | LIPG (0.49) | LIPGEPHX2MEN1KMT2AHTT | |
| SCHEMBL4308178 | 0.87 | LIPG (0.44) | LIPGEPHX2MEN1KMT2AHTT | |
| SCHEMBL3639331 | 0.83 | KMT2A (0.45) | MEN1KMT2AHTTSMN1; SMN2HPGD | |
| SCHEMBL3639332 | 0.83 | KMT2A (0.45) | MEN1KMT2AHTTSMN1; SMN2HPGD | |
| SCHEMBL14661034 | 0.83 | LIPG (0.45) | LIPGEPHX2MEN1KMT2AHTT | |
| SCHEMBL995999 | 0.83 | LIPG (0.45) | LIPGMEN1KMT2AHTTLMNA | |
| SCHEMBL3736416 | 0.80 | EPHX2 (0.46) | EPHX2MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1396040 | 0.79 | LIPG (0.42) | LIPGEPHX2MEN1KMT2AHTT | |
| SCHEMBL3702387 | 0.79 | KMT2A (0.41) | MEN1KMT2AHTTSMN1; SMN2HPGD | |
| SCHEMBL3702385 | 0.79 | KMT2A (0.41) | MEN1KMT2AHTTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029112-B2 | Ketoreductase-mediated stereoselective route to alpha chloroalcohols | CODEXIS, INC. (US) | 2015-05-12 | — | — | US | claimed |
| WO-2013014633-A1 | PROCESS FOR PREPARATION OF ATAZANAVIR OR ITS BISULFATE SALT | RANBAXY LABORATORIES LIMITED (IN) | 2013-01-31 | — | — | WO | claimed |
| EP-2446025-A2 | KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS | Codexis, Inc. (US) | 2012-05-02 | — | — | EP | claimed |
| WO-2013014633-A1 | PROCESS FOR PREPARATION OF ATAZANAVIR OR ITS BISULFATE SALT | RANBAXY LABORATORIES LIMITED (IN) | 2013-01-31 | — | — | WO | disclosed |
| EP-2446025-A2 | KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS | Codexis, Inc. (US) | 2012-05-02 | — | — | EP | disclosed |