Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759563 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDTP53NPC1RAB9A | |
| SCHEMBL27123909 | 0.89 | CCNA2 (0.42) | ALDH1A1HPGDTP53CCNA2CDK2 | |
| SCHEMBL30759548 | 0.88 | CCNA2 (0.45) | ALDH1A1HPGDCCNA2CDK2CCNA1 | |
| SCHEMBL27123716 | 0.88 | CCNA2 (0.45) | ALDH1A1HPGDCCNA2CDK2CCNA1 | |
| SCHEMBL30759596 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDTP53NPC1RAB9A | |
| SCHEMBL27120696 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDTP53NPC1RAB9A | |
| SCHEMBL12046658 | 0.84 | PDE4B (0.45) | ALDH1A1HPGDTP53CCNA2CDK2 | |
| SCHEMBL12046673 | 0.83 | CCNA2 (0.47) | ALDH1A1HPGDTP53NPC1CCNA2 | |
| SCHEMBL30759580 | 0.82 | CCNA2 (0.47) | ALDH1A1HPGDTP53CCNA2CDK2 | |
| SCHEMBL27122940 | 0.82 | CCNA2 (0.47) | ALDH1A1HPGDTP53CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |