Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859135 | 0.88 | — | — | |
| SCHEMBL14890131 | 0.88 | — | — | |
| SCHEMBL8135004 | 0.88 | — | — | |
| Bicarbonate SCHEMBL28318899 | 0.80 | GRIK1 (0.35) | GRIK1GRIK2FFAR3ALDH1A1TDP1 | |
| Bicarbonate SCHEMBL28318932 | 0.78 | GRIK1 (0.34) | GRIK1GRIK2FFAR3GABRR1 | |
| Bicarbonate SCHEMBL28602441 | 0.78 | GABRR1 (0.33) | FFAR3GABRR1MTNR1AMTNR1BLCK | |
| Bicarbonate SCHEMBL20423492 | 0.78 | GABRR1 (0.33) | FFAR3GABRR1MTNR1AMTNR1BLCK | |
| Bicarbonate SCHEMBL9752391 | 0.77 | KDM4E (0.41) | GRIK1GRIK2FFAR3ALDH1A1TDP1 | |
| SCHEMBL4509728 | 0.73 | — | — | |
| Bicarbonate SCHEMBL10996733 | 0.72 | GRIK2 (0.39) | GRIK1GRIK2FFAR3ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4439759-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | Ningde Amperex Technology Limited (CN) | 2024-10-02 | — | — | EP | disclosed |
| US-20240322170-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2024-09-26 | — | — | US | disclosed |
| EP-4310934-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE USING SAME | NingDe Amperex Technology Limited (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-20240006597-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE USING SAME | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2024-01-04 | — | — | US | disclosed |
| EP-4300615-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC APPARATUS | Ningde Amperex Technology Limited (CN) | 2024-01-03 | — | — | EP | disclosed |
| US-20230420687-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2023-12-28 | — | — | US | disclosed |