Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403101 | 0.87 | — | — | |
| SCHEMBL21352 | 0.87 | — | — | |
| Glycolic Acid SCHEMBL7723109 | 0.86 | FFAR3 (0.38) | KDM4EATMALDH1A1FFAR3TDP1 | |
| Ammonia Solution, Strong SCHEMBL9634137 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL28439915 | 0.83 | — | — | |
| Water SCHEMBL28328303 | 0.83 | — | — | |
| Carbon Dioxide SCHEMBL27412182 | 0.81 | — | — | |
| Formic Acid SCHEMBL29463695 | 0.81 | ALDH1A1 (0.39) | KDM4EATMALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL28459730 | 0.80 | — | — | |
| Ethylene SCHEMBL21772405 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844065-B1 | LURE COMPOSITION | ATTRATEC GMBH (DE) | 2021-01-06 | — | — | EP | claimed |
| WO-1991000301-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXYALKENYL CARBONATES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | claimed |
| EP-2844065-B1 | LURE COMPOSITION | ATTRATEC GMBH (DE) | 2021-01-06 | — | — | EP | disclosed |
| EP-2844065-A2 | ATTRACTANT COMPOSITION | Attratec GmbH (DE) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013164426-A2 | ATTRACTANT COMPOSITION | ATTRATEC GMBH (DE) | 2013-11-07 | — | — | WO | disclosed |
| WO-1991000301-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXYALKENYL CARBONATES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | disclosed |