Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 11/20 | 0.37 |
| ▸ | PRKDC | P78527 | 10/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 9/20 | 0.37 |
| ▸ | ATM | Q13315 | 7/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.36 |
| ▸ | MELK | Q14680 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
| ▸ | SERPINA2 | P20848 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541718 | 1.00 | ATR (0.37) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL27133782 | 0.92 | PRKDC (0.38) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL21541901 | 0.92 | PRKDC (0.38) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL21541791 | 0.90 | ATR (0.39) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL27124103 | 0.90 | ATR (0.39) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL21541724 | 0.87 | PRKDC (0.40) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL21541832 | 0.87 | MET (0.34) | ATRATMMELKMTORPIK3CA | |
| SCHEMBL21541861 | 0.84 | PRKDC (0.44) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL21541741 | 0.83 | ATR (0.38) | ATRPRKDCATRIPATMPIK3CB | |
| SCHEMBL27127196 | 0.83 | ATR (0.38) | ATRPRKDCATRIPATMPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |