SCHEMBL2712974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2712428	0.91	PIK3CD (0.44)	PIK3CDL3MBTL1TGFBR1IDO1GRM5
	SCHEMBL2711897	0.90	PIK3CD (0.54)	PIK3CDL3MBTL1TGFBR1IDO1GRM5
	SCHEMBL2712834	0.89	PIK3CD (0.52)	PIK3CDL3MBTL1TGFBR1GRM5PIK3CA
	SCHEMBL2713223	0.83	PIK3CD (0.75)	PIK3CDPIK3CA
	SCHEMBL3774912	0.80	PIK3CD (0.59)	PIK3CDPIK3CA
	SCHEMBL2712521	0.77	PIK3CD (0.51)	PIK3CDL3MBTL1PIK3CAKDM4ENPC1
	SCHEMBL2712519	0.77	PIK3CD (0.72)	PIK3CDPIK3CA
	SCHEMBL2711628	0.76	PIK3CD (0.74)	PIK3CDPIK3CA
	SCHEMBL2710923	0.75	PIK3CD (0.59)	PIK3CDL3MBTL1TGFBR1PIK3CAALDH1A1
	SCHEMBL2713104	0.75	PIK3CD (0.62)	PIK3CDPIK3CAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.