Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyridoxal. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.88 |
| ▸ | LMNA | P02545 | 6/20 | 0.88 |
| ▸ | HPGD | P15428 | 5/20 | 0.88 |
| ▸ | MEN1 | O00255 | 3/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.88 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.88 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.85 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.85 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | ACP1 | P24666 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.68 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.68 |
| ▸ | PDXK | O00764 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridoxal SCHEMBL9559097 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL27627958 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL28454700 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL18726347 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL5498057 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL5051301 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL30616198 | 1.00 | KDM4E (0.88) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL8090165 | 0.98 | KDM4E (0.85) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL1065056 | 0.98 | KDM4E (0.85) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| Pyridoxal SCHEMBL6701817 | 0.98 | KDM4E (0.85) | KDM4EALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 16333 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081266-A | Recombinant O-acetyl-L-homoserine sulfhydryl transferase mutant, recombinant genetic engineering bacterium and application | — | 2026-05-26 | — | — | CN | claimed |
| CN-118547024-B | Ragliptin intermediate, preparation method and application thereof | Yikelai Biotechnology (Group) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122081234-A | Low-serum MSB1 suspension medium and chicken infectious anemia virus inactivated vaccine | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081135-A | Lactobacillus plantarum strain enriched in gamma-aminobutyric acid and application | — | 2026-05-26 | — | — | CN | claimed |
| CN-121574157-B | Bio-based flame-retardant ultraviolet-resistant polyvinyl alcohol composite material and preparation method thereof | 安徽建筑大学 | 2026-05-22 | — | — | CN | claimed |
| CN-122060698-A | Transaminase mutant with improved enzyme activity and application thereof | 杭州微远生物科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122063204-A | High performance liquid chromatography detection method for ergothioneine | 弈柯莱生物科技(集团)股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-120923607-B | Recombinant vector for expressing natural long sequence recombinant XVII type collagen, and preparation method and application thereof | 北京守正优合科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-117402862-B | L-lysine decarboxylase derived from Klebsiella grimontii and application thereof | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122036797-A | Method for efficiently preparing high-purity pyridoxal phosphate by continuous flow | 台州职业技术学院 | 2026-05-15 | — | — | CN | claimed |
| US-4547465-A | INCLUDING A QUATERNARY AMMONIUM COMPOUND WITH DISPERSION OF POLYMER AND PARTICLES; COHESION WEAR RESISTANCE | EASTMAN KODAK COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| WO-1985003356-A1 | ASSAY FOR IMMOBILIZED REPORTER GROUPS | MOLECULAR BIOSYSTEMS, INC. (US) | 1985-08-01 | — | — | WO | claimed |
| WO-1985002414-A1 | METHOD OF CATALYZING CHEMICAL REACTIONS | IGEN, INC. (US) | 1985-06-06 | — | — | WO | claimed |
| US-4450232-A | AUTOMATIC QUANTITATIVVE ANALYSIS; ME%DICAL DIAGNOSIS OF LIVER DISORDERS; MYOCARDIAL INFARCTION | EASTMAN KODAK COMPANY (US) | 1984-05-22 | — | — | US | claimed |
| EP-0106813-A2 | Pharmaceutical utilisation of 3-indolpyruvic acid | POLIFARMA S.p.A. (IT) | 1984-04-25 | — | — | EP | claimed |
| EP-0085954-A2 | Incorporation of pyridoxal phosphate in dry analytical elements for the determination of enzymes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-08-17 | — | — | EP | claimed |
| US-4336248-A | SUITABLE FOR BLOOD REPLACEMENTS | BIOTEST-SERUM-INSTITUT GMBH (DE) | 1982-06-22 | — | — | US | claimed |
| EP-0049475-A2 | Soluble stabilized enzymes | Modrovich, Ivan Endre (US) | 1982-04-14 | — | — | EP | claimed |
| US-4235962-A | REAGENTS COMPRISING ASPARATE, ALANINE, 2-OXOGLUTARATE AND REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE | THE DOW CHEMICAL COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| US-3974031-A | Process for producing L-cysteine or its derivatives | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1976-08-10 | — | — | US | claimed |