Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.65 |
| ▸ | SRC | P12931 | 6/20 | 0.62 |
| ▸ | KDR | P35968 | 5/20 | 0.62 |
| ▸ | KIT | P10721 | 2/20 | 0.62 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.62 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 2/20 | 0.62 |
| ▸ | FYN | P06241 | 2/20 | 0.62 |
| ▸ | RET | P07949 | 2/20 | 0.62 |
| ▸ | MET | P08581 | 2/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.62 |
| ▸ | LTK | P29376 | 2/20 | 0.62 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.62 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.62 |
| ▸ | BTK | Q06187 | 2/20 | 0.62 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.62 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.62 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822099 | 1.00 | EGFR (0.67) | EGFRERBB2SRCKDRKIT | |
| SCHEMBL30822056 | 0.97 | EGFR (0.70) | EGFRERBB2SRCKDRKIT | |
| SCHEMBL27136117 | 0.97 | EGFR (0.70) | EGFRERBB2SRCKDRKIT | |
| SCHEMBL24715214 | 0.89 | EGFR (0.56) | EGFRERBB2SRCKDRLCK | |
| SCHEMBL27140994 | 0.88 | EGFR (0.57) | EGFRKDR | |
| SCHEMBL30822103 | 0.88 | EGFR (0.57) | EGFRKDR | |
| SCHEMBL30822061 | 0.88 | EGFR (0.55) | EGFRERBB2SRCKDR | |
| SCHEMBL27138493 | 0.88 | EGFR (0.55) | EGFRERBB2SRCKDR | |
| SCHEMBL24714517 | 0.87 | EGFR (0.62) | EGFRKDR | |
| SCHEMBL30822073 | 0.87 | EGFR (0.62) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | claimed |
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | disclosed |