Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519643 | 0.93 | KDM4E (0.46) | KDM4ECYP1A2CYP2C19CYP2D6MAPK1 | |
| SCHEMBL438704 | 0.84 | L3MBTL1 (0.40) | KDM4EALDH1A1KMT2AMEN1PIK3CD | |
| SCHEMBL25075398 | 0.83 | KDM4E (0.46) | KDM4ECYP1A2CYP2C19CYP2D6MAPK1 | |
| SCHEMBL10045163 | 0.81 | CYP2C19 (0.48) | CYP1A2CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL10045158 | 0.81 | CYP2C19 (0.48) | CYP1A2CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL14829804 | 0.81 | TSHR (0.43) | CYP1A2CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL7067353 | 0.81 | KDM4E (0.44) | KDM4ECYP1A2CYP2C19CYP2D6MAPK1 | |
| SCHEMBL11932518 | 0.80 | KDM4E (0.39) | KDM4ECYP1A2CYP2C19CYP2D6MAPK1 | |
| SCHEMBL29343849 | 0.79 | KDM4E (0.38) | KDM4ECYP1A2CYP2C19CYP2D6MAPK1 | |
| SCHEMBL10045165 | 0.79 | CYP2C19 (0.46) | CYP1A2CYP2C19ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328230-A2 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |