Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142451 | 0.85 | KCNJ1 (0.42) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL27138160 | 0.84 | HDAC6 (0.36) | ALDH1A1CYP1A2JMJD6GAAHDAC6 | |
| SCHEMBL3309074 | 0.83 | CYP1A2 (0.40) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL23535249 | 0.82 | KMT2A (0.41) | KMT2ANPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL31389811 | 0.82 | MAPT (0.37) | KMT2AMAPTCYP1A2TP53 | |
| SCHEMBL31607767 | 0.82 | HDAC6 (0.36) | ALDH1A1HDAC6 | |
| SCHEMBL25686948 | 0.80 | CYP1A2 (0.39) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27146168 | 0.79 | KMT2A (0.38) | KMT2ACYP1A2TP53GAA | |
| SCHEMBL26969122 | 0.79 | HDAC6 (0.43) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2929174 | 0.75 | NPC1 (0.41) | KMT2ANPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |