Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27152580 | 0.84 | CA9 (0.38) | KMT2ALMNACA9GAA | |
| SCHEMBL27137687 | 0.79 | KMT2A (0.36) | KMT2ACYP1A2GAATP53 | |
| SCHEMBL28628118 | 0.76 | KMT2A (0.43) | KMT2ALMNAFAAHCYP1A2GAA | |
| SCHEMBL31389606 | 0.74 | KMT2A (0.44) | KMT2ALMNAFAAHCYP1A2GAA | |
| SCHEMBL3309074 | 0.74 | CYP1A2 (0.40) | KMT2ACYP1A2GAA | |
| SCHEMBL27152236 | 0.73 | KMT2A (0.46) | KMT2ALMNAFAAHCYP1A2GAA | |
| SCHEMBL28923147 | 0.73 | KMT2A (0.42) | KMT2ACA9FAAHCYP1A2GAA | |
| SCHEMBL28923148 | 0.73 | KMT2A (0.42) | KMT2ACA9FAAHCYP1A2GAA | |
| SCHEMBL30682082 | 0.72 | KMT2A (0.39) | KMT2AFAAHCYP1A2GAATP53 | |
| SCHEMBL27136905 | 0.71 | LMNA (0.42) | KMT2ALMNACA9GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |