Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23475146 | 1.00 | ESR1 (0.52) | ESR1KDM4EALDH1A1LMNAMCHR1 | |
| SCHEMBL21247839 | 0.90 | ESR1 (0.50) | ESR1KDM4EALDH1A1LMNAMCHR1 | |
| SCHEMBL20165412 | 0.88 | ESR1 (0.50) | ESR1KDM4EALDH1A1LMNACHRM2 | |
| SCHEMBL20165409 | 0.88 | ESR1 (0.50) | ESR1KDM4EALDH1A1LMNACHRM2 | |
| SCHEMBL23529265 | 0.87 | CHRM2 (0.58) | ESR1CHRM2CHRM3 | |
| SCHEMBL29669585 | 0.86 | CHRM2 (0.57) | ESR1CHRM2CHRM3 | |
| SCHEMBL21247990 | 0.85 | RAB9A (0.47) | ESR1KDM4EALDH1A1LMNAMCHR1 | |
| SCHEMBL20165043 | 0.85 | ESR1 (0.48) | ESR1KDM4EALDH1A1LMNAMCHR1 | |
| SCHEMBL20165040 | 0.85 | ESR1 (0.48) | ESR1KDM4EALDH1A1LMNAMCHR1 | |
| SCHEMBL20179666 | 0.85 | ESR1 (0.48) | ESR1KDM4EALDH1A1LMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577531-A1 | NOVEL SUBSTITUTED 2-CARBONYL-BENZOTHIOPHENE-6- CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024042152-A1 | NOVEL SUBSTITUTED 2-CARBONYL-BENZOTHIOPHENE-6- CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-02-29 | — | — | WO | disclosed |