Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.63 |
| ▸ | CCNH | P51946 | 15/20 | 0.63 |
| ▸ | CCNK | O75909 | 14/20 | 0.63 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.63 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.63 |
| ▸ | CDK9 | P50750 | 13/20 | 0.63 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.63 |
| ▸ | CDK2 | P24941 | 12/20 | 0.63 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271440 | 1.00 | CDK7 (0.63) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24087425 | 0.91 | CCNK (0.56) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24087428 | 0.87 | CCNK (0.52) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24087376 | 0.86 | CCNK (0.51) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL30439572 | 0.84 | CCNK (0.63) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL27123939 | 0.83 | CDK7 (0.44) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL26967519 | 0.83 | CDK7 (0.44) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24584481 | 0.81 | CDK7 (0.49) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24584483 | 0.81 | CDK7 (0.49) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL27128260 | 0.80 | CDK7 (0.43) | CDK7CCNHCCNKCDK12CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4295852-A2 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |