Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.49 |
| ▸ | CCNH | P51946 | 15/20 | 0.49 |
| ▸ | CCNK | O75909 | 12/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.49 |
| ▸ | CDK9 | P50750 | 11/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.49 |
| ▸ | CDK2 | P24941 | 10/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24584481 | 1.00 | CDK7 (0.49) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL26627069 | 0.84 | PRKCA (0.37) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL29083578 | 0.82 | CCNK (0.61) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24583188 | 0.82 | CCNK (0.61) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL30626194 | 0.82 | PRKCA (0.38) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL30626193 | 0.82 | PRKCA (0.38) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24588853 | 0.81 | CDK7 (0.39) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24584176 | 0.81 | CDK7 (0.39) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL29749461 | 0.81 | ATR (0.41) | ATRATRIP | |
| SCHEMBL24584411 | 0.81 | ATR (0.41) | ATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269402-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | GT Apeiron Therapeutics Limited (HK) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022134641-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |