Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 6/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720903 | 0.85 | USP7 (0.43) | USP7PADI4USP47MAPTKDM4E | |
| SCHEMBL3719648 | 0.84 | USP7 (0.43) | USP7PADI4USP47MAPTKDM4E | |
| SCHEMBL3715750 | 0.84 | USP7 (0.57) | USP7PADI4USP47L3MBTL1POLB | |
| SCHEMBL3723562 | 0.82 | USP47 (0.43) | USP7PADI4USP47MAPTKDM4E | |
| SCHEMBL27154247 | 0.81 | PDE7A (0.44) | USP7PADI4USP47MAPTKDM4E | |
| SCHEMBL3719961 | 0.81 | USP7 (0.40) | USP7PADI4USP47MAPTGAA | |
| SCHEMBL3717084 | 0.80 | USP7 (0.46) | USP7PADI4USP47MAPTTDP1 | |
| SCHEMBL3712491 | 0.78 | USP7 (0.56) | USP7PADI4USP47 | |
| SCHEMBL3719652 | 0.76 | USP7 (0.60) | USP7PADI4USP47MAPTKMT2A | |
| SCHEMBL27139432 | 0.76 | USP7 (0.73) | USP7PADI4USP47MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326327-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | Northwestern University (US) | 2024-02-28 | — | — | EP | claimed |
| WO-2022226402-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | NORTHWESTERN UNIVERSITY (US) | 2022-10-27 | — | — | WO | claimed |