Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP47 | Q96K76 | 2/20 | 0.43 |
| ▸ | USP7 | Q93009 | 7/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714784 | 0.85 | USP47 (0.48) | USP47USP7PADI4MAPTALDH1A1 | |
| SCHEMBL3720903 | 0.84 | USP7 (0.43) | USP47USP7PADI4MAPTALDH1A1 | |
| SCHEMBL3717084 | 0.83 | USP7 (0.46) | USP47USP7PADI4MAPTTDP1 | |
| SCHEMBL3715750 | 0.82 | USP7 (0.57) | USP47USP7PADI4TDP1MEN1 | |
| SCHEMBL3719648 | 0.82 | USP7 (0.43) | USP47USP7PADI4MAPTALDH1A1 | |
| SCHEMBL3719652 | 0.82 | USP7 (0.60) | USP47USP7PADI4MAPTALDH1A1 | |
| SCHEMBL3714971 | 0.81 | USP7 (0.48) | USP47USP7MAPTALDH1A1KDM4E | |
| SCHEMBL3719961 | 0.80 | USP7 (0.40) | USP47USP7PADI4MAPTALDH1A1 | |
| SCHEMBL3717484 | 0.79 | USP7 (0.41) | USP47USP7PADI4MAPTALDH1A1 | |
| SCHEMBL3712491 | 0.79 | USP7 (0.56) | USP47USP7PADI4PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | disclosed |