Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27154619 | 0.88 | KCNH2 (0.38) | DYRK1AKCNH2NR1D1ALDH1A1SCN9A | |
| SCHEMBL27150227 | 0.86 | DYRK1A (0.51) | DYRK1AKCNH2NR1D1NFATC1GSK3B | |
| Lithium Ion SCHEMBL27150758 | 0.85 | DYRK1A (0.53) | DYRK1AKCNH2NR1D1NFATC1GSK3B | |
| SCHEMBL27148440 | 0.81 | SCN9A (0.40) | SCN9AGABRA2 | |
| SCHEMBL27147154 | 0.80 | PTGER4 (0.38) | ALDH1A1KDM4EPTGER4 | |
| SCHEMBL15687563 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EPTGER4HTT | |
| SCHEMBL27112266 | 0.78 | CNR2 (0.42) | DYRK1AKCNH2NR1D1ALDH1A1SCN9A | |
| SCHEMBL27144321 | 0.74 | DYRK1A (0.53) | DYRK1AKCNH2NR1D1NFATC1GSK3B | |
| SCHEMBL27144309 | 0.74 | KCNH2 (0.39) | DYRK1AKCNH2NR1D1SCN9AAAK1 | |
| Lithium Ion SCHEMBL27153439 | 0.73 | KCNH2 (0.41) | DYRK1AKCNH2NR1D1SCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066027-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066027-A1 | NOVEL PAR-2 INHIBITORS | F2RL1, F2R, F2RL3 | DYRK1A 3175/4885KCNH2 2460/4885NR4A2 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.