Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213475 | 0.91 | SIRT2 (0.36) | FURINROCK2SIRT5SIRT1SIRT2 | |
| SCHEMBL19681567 | 0.89 | FURIN (0.39) | FURINSIRT5FAPMAP1LC3BNPY1R | |
| SCHEMBL15699736 | 0.84 | FURIN (0.40) | FURINSIRT5SIRT1MAP1LC3BNPY1R | |
| SCHEMBL25787504 | 0.84 | FURIN (0.40) | FURINSIRT5SIRT1MAP1LC3BNPY1R | |
| SCHEMBL30297062 | 0.83 | HTT (0.41) | FURINSIRT1SIRT2MAP1LC3BNPY1R | |
| SCHEMBL27447192 | 0.83 | FURIN (0.39) | FURINROCK2NPY1RNPY4RKLKB1 | |
| SCHEMBL22138596 | 0.83 | FURIN (0.39) | FURINROCK2NPY1RNPY4RKLKB1 | |
| SCHEMBL20705515 | 0.83 | FURIN (0.39) | FURINROCK2NPY1RNPY4RKLKB1 | |
| SCHEMBL30988370 | 0.83 | FURIN (0.41) | FURINKLKB1HTT | |
| SCHEMBL30874648 | 0.83 | TLR2 (0.41) | SIRT5SIRT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043319-A1 | ANTIBODY-DRUG COMPLEX | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-02-29 | — | — | WO | disclosed |