SCHEMBL2714926

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2716227	0.91	SCN9A (0.57)	SCN9AMAPTGSK3BRIPK1LMNA
	SCHEMBL2714475	0.90	SCN9A (0.58)	SCN9AMAPTGSK3BRIPK1SMN1; SMN2
	SCHEMBL2717433	0.90	RIPK1 (0.45)	SCN9ARIPK1
	SCHEMBL2716783	0.89	SCN9A (0.42)	SCN9ARIPK1ADORA3PSEN1PSEN2
	SCHEMBL2715328	0.89	SCN9A (0.56)	SCN9AMAPTGSK3BRIPK1LMNA
	SCHEMBL2719099	0.87	GSK3B (0.61)	SCN9AMAPTGSK3BLMNAALDH1A1
	SCHEMBL2714832	0.87	SCN9A (0.50)	SCN9AMAPTGSK3BADORA3SMN1; SMN2
	SCHEMBL2718389	0.84	MAPT (0.40)	SCN9AMAPTGSK3BRIPK1SMN1; SMN2
	SCHEMBL2713770	0.84	SCN9A (0.51)	SCN9AMAPTGSK3BRIPK1ADORA3
	SCHEMBL18266570	0.84	SCN9A (0.41)	SCN9ARIPK1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.