⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27149280 | 1.00 | — | — | |
| SCHEMBL25349219 | 1.00 | — | — | |
| SCHEMBL29207293 | 0.79 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL25540513 | 0.77 | — | — | |
| SCHEMBL27150030 | 0.76 | NCF1 (0.30) | — | |
| SCHEMBL27150031 | 0.76 | NCF1 (0.30) | — | |
| SCHEMBL27150029 | 0.76 | NCF1 (0.30) | — | |
| SCHEMBL25349499 | 0.74 | — | — | |
| SCHEMBL25346368 | 0.74 | — | — | |
| SCHEMBL27137581 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596551-A1 | COMPOUNDS WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | Trasveda Ltd. (KY) | 2025-08-06 | — | — | EP | disclosed |
| CN-118772151-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2024207892-A1 | COMPOUNDS HAVING ACTIVITY AGAINST KRAS-MUTANT TUMORS | 泰励生物科技（上海）有限公司 | 2024-10-10 | — | — | WO | disclosed |
| WO-2024067714-A1 | COMPOUNDS WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | 泰励生物科技（上海）有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117624170-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2024041606-A1 | COMPOUND WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | 泰励生物科技（上海）有限公司 | 2024-02-29 | — | — | WO | disclosed |