SCHEMBL27149366

SCHEMBL27149366

CCCCCCCCC(O)(CCCO)CCCCCCCC.CCCCCCCCCCCCC(O)(CCCO)CCCCCCCCCCCC

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.65
ALDH1A1 P00352 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
HSD17B10 Q99714 1/20 0.65
TSHR P16473 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.60
FDPS P14324 8/20 0.45
GGPS1 O95749 5/20 0.45
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27141840 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL1034608 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL28529788 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL11797444 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL19661642 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL10605396 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL31243262 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL9055861 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL1035585 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL22814372 1.00 LMNA (0.65) LMNAALDH1A1MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326235-A2 CATIONIC LIPIDS AND COMPOSITIONS THEREOF Generation Bio Co. (US) 2024-02-28 EP disclosed