Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416496 | 0.84 | ALDH1A1 (0.78) | GBA1ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL27149792 | 0.78 | GBA1 (0.56) | GBA1ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL29650644 | 0.75 | LATS1 (0.61) | ALDH1A1 | |
| SCHEMBL27149794 | 0.73 | GBA1 (0.55) | GBA1ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL18354436 | 0.73 | GBA1 (1.00) | GBA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19286343 | 0.71 | CYP1A2 (0.74) | GBA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7278023 | 0.71 | MEN1 (0.87) | GBA1ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL20273653 | 0.70 | CYP1A2 (1.00) | GBA1ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL15289677 | 0.70 | TSHR (0.77) | GBA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7278041 | 0.70 | GBA1 (0.71) | GBA1ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328230-A2 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |