Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WIZ | O95785 | 6/20 | 0.86 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 7/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23532866 | 0.93 | WIZ (1.00) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23532870 | 0.93 | WIZ (1.00) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23532816 | 0.92 | WIZ (0.91) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23532949 | 0.92 | WIZ (0.91) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23532813 | 0.92 | WIZ (0.91) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23546021 | 0.91 | WIZ (0.90) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23532605 | 0.91 | WIZ (0.80) | WIZCRBNIKZF3IKZF2GSPT1 | |
| SCHEMBL27144607 | 0.91 | WIZ (0.71) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23533018 | 0.90 | WIZ (0.86) | WIZCRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL23533015 | 0.90 | WIZ (0.86) | WIZCRBNIKZF3IKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076650-B1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2024-02-28 | — | — | EP | claimed |
| CN-114828959-B | 3- (5-methoxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivative and application thereof | 诺华股份有限公司 | 2024-04-02 | — | — | CN | disclosed |