Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.69 |
| ▸ | QPCT | Q16769 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183410 | 1.00 | TBXAS1 (0.69) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL23746470 | 0.93 | TBXAS1 (0.74) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL28712305 | 0.93 | TBXAS1 (0.74) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL28720416 | 0.93 | TBXAS1 (0.74) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL16299531 | 0.92 | TBXAS1 (0.71) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL29109593 | 0.88 | TBXAS1 (0.71) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28286843 | 0.86 | TBXAS1 (0.68) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL10903412 | 0.83 | TBXAS1 (0.58) | TBXAS1QPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL13256613 | 0.83 | QPCT (0.65) | TBXAS1QPCTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4059134 | 0.82 | TBXAS1 (1.00) | TBXAS1QPCTPRKCILMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066072-A1 | CLOSTRODIOIDES DIFFICILE TREATMENT | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-02-29 | — | — | US | disclosed |