Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 7/20 | 0.55 |
| ▸ | USP47 | Q96K76 | 3/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341250 | 0.75 | PDE7A (0.58) | USP7USP47PDE7ATDP1ITGB2 | |
| SCHEMBL27153325 | 0.74 | USP7 (0.51) | USP7PDE7ATDP1SMN1; SMN2LMNA | |
| SCHEMBL2681824 | 0.73 | USP7 (0.70) | USP7USP47PDE7ATDP1ITGB2 | |
| SCHEMBL17819801 | 0.72 | USP7 (0.51) | USP7USP47PDE7ATDP1ITGB2 | |
| SCHEMBL2680096 | 0.72 | USP7 (0.80) | USP7USP47ITGB2ICAM1ITGAL | |
| SCHEMBL2681288 | 0.71 | USP7 (1.00) | USP7USP47ITGB2ICAM1ITGAL | |
| SCHEMBL30031458 | 0.71 | USP7 (1.00) | USP7USP47ITGB2ICAM1ITGAL | |
| SCHEMBL3717383 | 0.70 | USP7 (1.00) | USP7USP47PDE7ATDP1ITGB2 | |
| SCHEMBL3715754 | 0.70 | USP7 (0.72) | USP7USP47PDE7ATDP1ITGB2 | |
| SCHEMBL2681421 | 0.69 | USP7 (0.78) | USP7USP47 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326327-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | Northwestern University (US) | 2024-02-28 | — | — | EP | claimed |