Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 12/20 | 0.72 |
| ▸ | USP47 | Q96K76 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716798 | 0.91 | USP7 (0.59) | USP7USP47KDM4EMAPTALDH1A1 | |
| SCHEMBL3712957 | 0.87 | USP7 (0.58) | USP7USP47PADI4 | |
| SCHEMBL3717383 | 0.84 | USP7 (1.00) | USP7USP47KDM4EMAPTALDH1A1 | |
| SCHEMBL3717157 | 0.82 | USP7 (0.69) | USP7USP47MAPTTDP1ITGB2 | |
| SCHEMBL3714971 | 0.81 | USP7 (0.48) | USP7USP47KDM4EMAPTALDH1A1 | |
| SCHEMBL3719652 | 0.80 | USP7 (0.60) | USP7USP47MAPTALDH1A1TDP1 | |
| SCHEMBL3719301 | 0.80 | USP7 (0.48) | USP7USP47PDE7A | |
| SCHEMBL3717084 | 0.79 | USP7 (0.46) | USP7USP47MAPTTDP1PDE7A | |
| SCHEMBL3715105 | 0.78 | USP7 (0.45) | USP7USP47KDM4EMAPTALDH1A1 | |
| SCHEMBL3715750 | 0.78 | USP7 (0.57) | USP7USP47TDP1PDE7APADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326327-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | Northwestern University (US) | 2024-02-28 | — | — | EP | claimed |
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |
| EP-4326327-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | Northwestern University (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | disclosed |