SCHEMBL2715217

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714398	0.92	MAPT (0.46)	MAPTGSK3BSCN9AKCNB1KCNA5
	SCHEMBL2718525	0.92	CYP3A4 (0.40)	MAPTGSK3BSCN9ATAS1R3TAS1R1
	SCHEMBL2716382	0.91	HPGD (0.45)	MAPTGSK3BSCN9AKCNB1KCNA5
	SCHEMBL2716628	0.91	SCN9A (0.47)	MAPTGSK3BSCN9AKCNB1KCNA5
	SCHEMBL15351457	0.89	MAPT (0.47)	MAPTGSK3BSCN9AKCNB1KCNA5
	SCHEMBL2715612	0.88	ACACB (0.41)	KCNB1
	SCHEMBL2717410	0.88	MAPT (0.61)	MAPTGSK3BSCN9AKCNB1KCNA5
	SCHEMBL2713734	0.88	SCN9A (0.46)	MAPTGSK3BSCN9AKCNB1KCNA5
	SCHEMBL18266498	0.86	CYP3A4 (0.40)	MAPTSCN9ATAS1R3TAS1R1NPC1
	SCHEMBL2715896	0.85	SCN9A (0.50)	MAPTGSK3BSCN9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.