SCHEMBL2718525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266498	0.94	CYP3A4 (0.40)	CYP3A4AAK1ACACBTAS1R3TAS1R1
	SCHEMBL2715217	0.92	MAPT (0.47)	TAS1R3TAS1R1MAPTGSK3BNPC1
	SCHEMBL2716819	0.91	HPGD (0.46)	CYP3A4AAK1ACACBTAS1R3TAS1R1
	SCHEMBL2719407	0.91	CYP3A4 (0.42)	CYP3A4AAK1ACACBTAS1R3TAS1R1
	SCHEMBL2715612	0.89	ACACB (0.41)	ACACB
	SCHEMBL28093959	0.89	MAPT (0.37)	CYP3A4AAK1ACACBTAS1R3TAS1R1
	SCHEMBL15350509	0.89	TAS1R3 (0.42)	CYP3A4AAK1ACACBTAS1R3TAS1R1
	SCHEMBL2715810	0.88	ACACB (0.50)	CYP3A4AAK1ACACBTAS1R3TAS1R1
	SCHEMBL2717539	0.87	SCN9A (0.37)	ACACBTAS1R3TAS1R1MAPTGSK3B
	SCHEMBL2714148	0.85	SCN9A (0.41)	ACACBMAPTGSK3BALDH1A1SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.