Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994546 | 1.00 | MAOB (0.54) | MAOBMAOARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27346267 | 1.00 | MAOB (0.54) | MAOBMAOARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27838264 | 0.90 | MAOB (0.54) | MAOBMAOARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19994542 | 0.86 | MAOB (0.55) | MAOBMAOARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19994654 | 0.86 | MAOB (0.55) | MAOBMAOARAB9ANPC1MAPT | |
| SCHEMBL19994543 | 0.86 | MAOB (0.55) | MAOBMAOARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19994634 | 0.86 | MAOB (0.55) | MAOBMAOA | |
| SCHEMBL19994591 | 0.86 | MAOB (0.55) | MAOBMAOARAB9ANPC1LMNA | |
| SCHEMBL19994638 | 0.86 | MAOB (0.55) | MAOBMAOA | |
| SCHEMBL19026545 | 0.86 | MAOB (0.43) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |