SCHEMBL2715331

SCHEMBL2715331

CC(=O)C1(C(C)=O)CCC(=O)N1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.32
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3344771 0.80 CRBN (0.32) CRBN
SCHEMBL8903294 0.77 CRBN (0.32) CRBN
SCHEMBL20703829 0.77 CRBN (0.30) CRBN
SCHEMBL14828715 0.76 PARP1 (0.32) CRBNPARP1
SCHEMBL783379 0.73
SCHEMBL8904269 0.72 POLB (0.44) CRBN
SCHEMBL7271137 0.70
SCHEMBL23418116 0.67 FFAR3 (0.37) CRBNPARP1
SCHEMBL1847937 0.67 FFAR3 (0.37) CRBNPARP1
SCHEMBL2637028 0.67 FFAR3 (0.37) CRBNPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445874-B1 PROCESS OF PREPARATION OF 2-ACETYL-1-PYRROLINE AND A STABLE PRECURSOR THEREOF, ISOTOPICALLY LABELLED OR NOT CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) 2017-11-29 EP disclosed
EP-2445874-A1 METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED Centre National De La Recherche Scientifique CNRS (FR) 2012-05-02 EP disclosed
WO-2010149744-A1 METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-12-29 WO disclosed