Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.68 |
| ▸ | AKT1 | P31749 | 3/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | AKT2 | P31751 | 1/20 | 0.56 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214004 | 1.00 | HSD17B10 (0.71) | HSD17B10CHRM1HDAC8AKT1PLAU | |
| SCHEMBL11226904 | 1.00 | HSD17B10 (0.71) | HSD17B10CHRM1HDAC8AKT1PLAU | |
| Hydrochloric Acid SCHEMBL27547045 | 0.98 | HDAC8 (0.69) | HSD17B10CHRM1HDAC8AKT1PLAU | |
| Hydrochloric Acid SCHEMBL6898277 | 0.98 | HDAC8 (0.69) | HSD17B10CHRM1HDAC8AKT1PLAU | |
| SCHEMBL6161206 | 0.89 | HDAC8 (0.66) | HSD17B10CHRM1HDAC8AKT1PLAU | |
| SCHEMBL7371854 | 0.88 | DPP7 (0.57) | HSD17B10CHRM1HDAC8DPP4 | |
| SCHEMBL7372150 | 0.88 | DPP7 (0.57) | HSD17B10CHRM1HDAC8DPP4 | |
| SCHEMBL5891540 | 0.88 | HDAC8 (0.60) | HSD17B10CHRM1HDAC8OPRD1DPP4 | |
| SCHEMBL29496465 | 0.87 | CHRM1 (0.58) | HSD17B10CHRM1HDAC8OPRD1DPP4 | |
| Hydrochloric Acid SCHEMBL5891327 | 0.86 | HDAC8 (0.61) | HSD17B10CHRM1HDAC8OPRD1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-07-04 | — | — | US | disclosed |
| EP-4326724-A1 | COMPOUND AS ADENOSINE A2A RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2024-02-28 | — | — | EP | disclosed |
| CN-117120443-A | Compounds as adenosine A2a receptor antagonists and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2023-11-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ADORA2A, ADORA1, ADORA2B | HSD17B10 2827/4885CHRM1 137/4885HDAC8 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.