SCHEMBL2715529

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2716842	0.93	NR3C2 (0.52)	SCN9AMAPTGSK3BNTRK1PPARD
	SCHEMBL2716720	0.88	SCN9A (0.57)	SCN9AMAPTGSK3BP2RX7ROS1
	SCHEMBL2715370	0.86	MAPT (0.51)	SCN9AMAPTGSK3BP2RX7
	SCHEMBL2715551	0.84	MAPT (0.51)	SCN9AMAPTGSK3BROS1ALK
	SCHEMBL2714991	0.84	MAPT (0.56)	SCN9AMAPTGSK3BKDM1AHDAC1
	SCHEMBL2715403	0.84	SCN9A (0.59)	SCN9AMAPTGSK3BKDM1AHDAC1
	SCHEMBL2717704	0.84	SCN9A (0.57)	SCN9AMAPTGSK3BNR3C2
	SCHEMBL2715620	0.83	SCN9A (0.56)	SCN9AMAPTGSK3BKDM1AHDAC1
	SCHEMBL2717522	0.83	SCN9A (0.51)	SCN9AMAPTGSK3BPPARGP2RX7
	SCHEMBL2716052	0.83	GSK3B (0.61)	SCN9AMAPTGSK3BNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.