SCHEMBL2715620

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715403	0.94	SCN9A (0.59)	SCN9AMAPTGSK3BROS1MLYCD
	SCHEMBL2718344	0.89	NAMPT (0.51)	SCN9ANAMPTROS1MLYCDKDM1A
	SCHEMBL2715156	0.87	NAMPT (0.49)	SCN9ANAMPTROS1MLYCDKDM1A
	SCHEMBL2717704	0.87	SCN9A (0.57)	SCN9AMAPTGSK3BMLYCDCYP3A4
	SCHEMBL2715297	0.84	SCN9A (0.55)	SCN9ANAMPTMLYCDTACR1CYP3A4
	SCHEMBL2717667	0.84	GSK3B (0.53)	MAPTGSK3BNAMPT
	SCHEMBL2714394	0.83	SCN9A (0.57)	SCN9AMAPTGSK3BKDM1AHDAC1
	SCHEMBL2715529	0.83	SCN9A (0.52)	SCN9AMAPTGSK3BROS1KDM1A
	SCHEMBL2716842	0.82	NR3C2 (0.52)	SCN9AMAPTGSK3BROS1KDM1A
	SCHEMBL27913626	0.82	NAMPT (0.52)	NAMPTMLYCDKDM1AHDAC1TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.