SCHEMBL2715549

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714769	0.92	ACACB (0.50)	ACACBPDE2AGPR139LMNANTRK1
	SCHEMBL2715705	0.92	ACACB (0.50)	ACACBPDE2AGPR139LMNANTRK1
	SCHEMBL15350971	0.90	TRPV1 (0.48)	PDE2AGPR139NTRK1MAPK1GSK3A
	SCHEMBL2716316	0.89	GPR139 (0.52)	ACACBGPR139LMNANTRK1MAPK1
	SCHEMBL2717402	0.89	ACACB (0.53)	ACACBPDE2ALMNAMAPK1GSK3A
	SCHEMBL2719067	0.89	ACACB (0.58)	ACACBPDE2AGPR139LMNAMAPK1
	SCHEMBL2718234	0.88	PDE2A (0.52)	ACACBPDE2ALMNAMAPK1GSK3A
	SCHEMBL2718235	0.88	PDE2A (0.52)	ACACBPDE2ALMNAMAPK1GSK3A
	SCHEMBL2714263	0.87	GSK3B (0.61)	ACACBPDE2AGSK3AGSK3B
	SCHEMBL2718591	0.85	PDE2A (0.52)	PDE2AGPR139MAPK1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.