SCHEMBL2716080

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715157	0.90	RIPK1 (0.54)	SCN9ARIPK1LMNAKMT2ANPSR1
	SCHEMBL2715398	0.89	SCN9A (0.61)	SCN9ARIPK1LMNAKMT2A
	SCHEMBL2718663	0.88	RIPK1 (0.47)	SCN9ARIPK1LMNAKMT2ANPSR1
	SCHEMBL2716240	0.86	POLB (0.46)	SCN9ARIPK1KMT2A
	SCHEMBL2717869	0.85	RIPK1 (0.54)	SCN9ARIPK1
	SCHEMBL2714394	0.85	SCN9A (0.57)	SCN9ARIPK1LMNAKMT2ANPSR1
	SCHEMBL18266345	0.85	SCN9A (0.48)	SCN9ARIPK1PPARGPPARDPPARA
	SCHEMBL2716475	0.84	KMT2A (0.55)	SCN9ALMNAKMT2A
	SCHEMBL2714077	0.83	SCN9A (0.50)	SCN9APPARDPPARA
	SCHEMBL2716374	0.83	SCN9A (0.49)	SCN9ARIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.