SCHEMBL2716299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16234576	0.92	SCN9A (0.40)	SCN9AGSK3BMAPTAAK1PTGES
	SCHEMBL2717266	0.91	SCN9A (0.48)	SCN9AGSK3BMAPTAAK1PTGES
	SCHEMBL2718389	0.90	MAPT (0.40)	SCN9AGSK3BMAPTAAK1PTGES
	SCHEMBL2715879	0.90	CNR2 (0.36)	SCN9AGSK3BPTGESMMP13GSK3A
	SCHEMBL2715892	0.88	TSHR (0.38)	SCN9AGSK3BMAPTPTGESMMP13
	SCHEMBL2716005	0.86	GSK3B (0.39)	GSK3BMMP13GSK3ACNR2ALDH1A1
	SCHEMBL2715703	0.85	PTGES (0.46)	SCN9AGSK3BMAPTPTGESKCNH2
	SCHEMBL2715119	0.85	SCN9A (0.40)	SCN9AGSK3BMAPTAAK1
	SCHEMBL27913546	0.85	CNR2 (0.39)	SCN9AMMP13ROCK2CNR2ALDH1A1
	SCHEMBL2717884	0.83	ADORA2A (0.41)	MMP13ROCK2CNR2CSF1RMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.