Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271551 | 0.92 | MRGPRX4 (0.45) | MRGPRX4HTTDDR1P2RX7MAPT | |
| SCHEMBL271329 | 0.88 | MAPT (0.38) | MRGPRX4MAPTNOTUMGAA | |
| SCHEMBL270928 | 0.88 | NOTUM (0.35) | MRGPRX4MAPTNOTUM | |
| SCHEMBL271678 | 0.85 | S1PR4 (0.42) | MRGPRX4PKMGAAS1PR4 | |
| SCHEMBL271411 | 0.85 | GRM4 (0.43) | HTTPTGDR2GAAHSP90AA1HSP90B1 | |
| SCHEMBL271510 | 0.83 | P2RX7 (0.41) | MRGPRX4P2RX7HSP90AA1HSP90B1 | |
| SCHEMBL270266 | 0.82 | MCL1 (0.41) | MRGPRX4DDR1MAPTNOTUMGAA | |
| SCHEMBL270825 | 0.82 | POLQ (0.41) | MAPTPTGDR2 | |
| SCHEMBL269850 | 0.81 | NOTUM (0.39) | MRGPRX4P2RX7NOTUMCCR2PTGDR2 | |
| SCHEMBL271267 | 0.81 | NOTUM (0.37) | MRGPRX4DDR1PKMNOTUMPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | MRGPRX4 1864/4885HTT 1457/4885DDR1 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.